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KMID : 0378019710140080063
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New Medical Journal
1971 Volume.14 No. 8 p.63 ~ p.68
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The Effects of Monosodium Glutamate on the Developing Rat Fetuses
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李洸鎬/Lee, Kwang Ho
白相豪/羅鳳鎭/張家鏞/Baik, Sang Ho/Rha, Bong Jin/Chang, Ka Yong
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Abstract
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As one of the series studying the effect of monosodium glutamate on the developing albino rat fetuses, the external abnormalities, body weight of fetuses, and increase of body weight and numbers of corpus luteum of mothers were observed.
41 primiparous Sprague-Dawley albino rats were injected monosodium glutamate intraperitoneally with the doses ranging from 1 to 3gm/kg of body weights on the 7th and 1lth day of estation. On the 22nd day of gestation, all the rats were sacrificed and compared with normal control groups.
No specific external abnormalities were found on the 414 fetuses, but significant fetal weight increase in comparison with normal control groups were noticed.
Twentyfive per cent of the pregnant rats delivered their litters on the 22nd day of gestation, that means the reduction of the gestation period. No differences, however, were observed between both of the body weights of fetuses of 22nd day of gestation and delivered newborns.
Increasing rate in per cent of maternal body weight and numbers of corpus luteum showed no differences compared with the normal control groups.
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